ABSTRACT
Fine Needle Aspiration (FNA) is a well-established and widely accepted procedure in the evaluation of breast masses. Fine needle aspiration cytology can be performed as an OPD procedure. It is less traumatic to the patient as compared to surgical biopsy, is cost effective, and can provide rapid results on the same day. Therefore, it can be used as an initial diagnostic procedure for male breast lesions. The aim of our study was to determine the efficacy of Fine-Needle Aspiration Cytology (FNAC) in the diagnosis of male breast lesions and categorization of these lesions as per IAC Categories.METHODSThe present study included 50 cases of male breast lesions presented in the department of the pathology. Fine-Needle Aspiration Cytology (FNAC) was done and slides were stained with MGG and PAP. Findings were analysed by two pathologists independently. Cyto-histological correlation was done in cases wherever possible. Sensitivity and specificity were calculated.RESULTSA total of 50 cases of male breast lesions which had undergone FNAC was analysed in this study. Histopathological examination was available in 10 cases. Gynecomastia C2 (88%) was found to be the most common entity followed by acute on chronic suppurative pathology (4%). There was no false positive or false negative finding. FNAC had a sensitivity and specificity and diagnostic accuracy of 100% for male breast lesions.CONCLUSIONSFNAC is the excellent sensitive and specific diagnostic tool for the assessment of breast lesions in males. Hence, we strongly recommend the use of FNAC as the first-line investigation in the clinical evaluation of male breast lumps.
ABSTRACT
Pap smear is an important tool to assess, follow up and monitor the diagnosed cases of carcinoma cervix. In the present study we have taken cases which were already diagnosed of cervical carcinoma, took radiotherapy and chemotherapy and surgical intervention as whole or one entity. These cases were assessed for cytological features of therapy induced changes, recurrence of carcinoma or no intraepithelial lesion or malignancy (NILM). Aim: The aim of the present study is to study the effects of radiotherapy and chemotherapy on squamous epithelial cells and to study the rate of recurrence of Squamous cell carcinoma after completion of chemotherapy and radiotherapy. Methods: Total No. of 50 cases were taken ranging from 27 yrs. to 70 yrs. age group who presented at tertiary care hospitals in northern part of India for about 1.5 year duration where facilities of radio and chemotherapy and surgical oncology was present. Results: In the present study, nucleomegaly was found to be most common finding in 46 (92%) of cases, next came vacuolisation both cytoplasmic and nuclear however nuclear vacuolisation outnumbered cytoplasmic. Conclusion: The total no. of cases having malignant or dysplastic cells varied with age and found to be higher in advancing age groups although in younger age group (20-29) having only one case was found to be positive for malignant/dysplastic cells.